Multiple Myeloma Treament

It is always recommended that a second opinion be asked for before proceeding with any type of Multiple Myeloma treatment. A series of blood and urine tests will be called for before any diagnosis. And, usually, if an irregular protein called the Bence Jones protein is found in the urine test, a bone marrow biopsy will either confirm or deny if the disease is present. If you or a loved one has received an Multiple Myeloma Prognosis, there are many options available for Myeloma survival and well being

Multiple Myeloma Treatment Options for Myeloma Cancer Patients

There are many Myeloma Cancer drug and treatment options available to Multiple Myeloma patients including; chemotherapymyeloma stem cell transplantation, sometimes including what’s called “piggy back transplants” (one right after another), radiation and medications. Clinical trials are continually in progress as researchers are constantly trying to find out how to cure Multiple Myeloma cancer or at least contain the plasma cell myeloma to increase Myeloma survival and well being for patients.

Numerous new medications are being put into trial status. Some combinations of medications are found quite by accident. Multiple Myeloma treatments and research have been found to benefit other types of cancers as well as myeloma itself.

Myeloma Survival: Myeloma Cancer Drug and Treatment Options

Myeloma survival and well being is dependent on the right treatment for the individual Myeloma Cancer patient. Often combinations of drugs and treatments are used to combat the cancer and ease the patients symptoms.

  • Pomalyst® (pomalidomide) is the newest oral immun­omodulatory drug (IMiD®). Approved by the FDA in 2013, Pomalyst is chemically related to thalidomide and lenalidomide, which was approved by the FDA in 2006, but Pomalyst has been enhanced to be more effective.
  • Kyprolis™ (carfilzomib) is a next-generation proteasome inhibitor. Kyprolis is FDA-approved for the treatment of patients with multiple myeloma (MM) who have received at least two prior therapies, including bortezomib and an immunomodulatory agent (IMiD), and have demonstrated disease progression on or within 60 days of the completion of the last therapy.
  • Thalidomide is an immunomodulatory agent that enhances immune response, immune cell activity and inhibits inflammation. Thalidomide was one of the first Meyloma cancer drugs used for the treatment of Myeloma patients.
  • Revlimid, also known as Lenalidomide, is used in the treatment of multiple myeloma patients to promote immune systems responses.
  • Velcade, also known as Bortezomib, is used to stop growth of cancer cells and prevent the spreading of plasma cell myeloma in myeloma cancer patients.
  • Melphalan, also known as L-PAM or L-phenylalanine mustard, is used in myeloma cancer patients to destroy the plasma cell myeloma lesion or tumor.
  • Zometa, also known as Reclast or Zoledronic acid blocks the release of calcium in the bones in Myeloma cancer patients where the myeloma plasma has spread throughout the body.
  • Aredia, also known as Pamidronate decrease the increased risks for bone pain and bone fractures in Myeloma cancer patients.

Regular Pet Scans are requested to check for any lesions in the bone. A top of the head to bottom of the feet PetScan will be required as most bones in a person’s body contain bone marrow. A patient should ask for and retain a DVD of the PetScan.

A new test called Freelite or Serum Free Light Chain Assay is the latest and most efficient method in detecting irregularities in the bone marrow. In fact, it has been found that the Light Chain test can actually predict a relapse faster than the older method of blood tests. “Results obtained from typing of monoclonal proteins into IgG, A, or M types were comparable with results obtained by immunofixation-electrophoresis methods. Initial clinical studies, in multiple myeloma patients, indicated that Ig’{kappa}/Ig’{lambda} ratios were sometimes more sensitive than immunofixation electrophoresis, provided numerical results, and correlated with changes in disease” (Clinical Chemistry). For more information go to“Understanding Serum Free Light Chain Assays” by the IMF.

It has been recently discovered by Mayo Clinic researchers that Myeloma may not be just one type of cancer, but several different types and may cause the use of different therapies and medications, according to each individual patient, in order to contain the cancerous plasma cells.

Multiple Myeloma Cancer has no known 100% cure. However, with the proper Multiple Myeloma treatments many myeloma cancer patients can lead normal lives by using various medications that are proving to be very successful in the containment of the plasma cancer cells and control of multiple myeloma symptoms.